1, NMR spectra were recorded on a Varian VNMRS spectrometer in CDCl, C NMR spectra. A sterol isolated from the roots of Amaranthus viridis has been assigned the structure 24-methylene-20- hydroxycholest-5,7-en-3β-ol. 12. Of 16 flavonoids related in structure with hyperin (4) and quercitrin (6), quercetin, isoquercitrin, rutin, myricetin and myricitrin also increased the BR in the standard medium, while kaempferol and luteorin decreased the BR in the standard medium. At the present time, 60 species of Amaranthus are documented with Amaranthus viridis popularly known as “tete” in Yoruba being the most widely cultivated vegetable *Corresponding author: Babatunde T. The present study was conducted to evaluate the phenolics, antioxidant and antimicrobial activities of leaf and seed extracts from an edible herb namely Amaranthus viridis L. The extract yields of active components, produced using pure and aqueous methanol, from the leaves and seeds ranged from 5.4 to 6.0 and 2.4 to 3.7%, respectively. Amaranthus viridis, A. retroflexus, A. hybridus, A. gracilis, A. gangeticus, A. paniculatus, and A. graecizans are wild types. (2010) reported the possibility of seed dispersal via ruminants. 51, No. extracts, hydroxy-β-sanshool (1b), xanthoxylin (2) and two quercetin glycosides, hyperin (4) and quercitrin (6), were found to increase the BR in a standard medium (2.1 mM Ca2+). All the extracts showed dose-dependent antiviral activities. proceedings of 54th ththe iier international conference, beijing, china, 13 january 2016, isbn: 978-93-82702-35-1 10 qualitative and quantitative phytochemical analysis and antioxidant potential of amaranthus viridis l. from pakistan 1sehrish sadia, 2zia ur rehman mashwani, 3humara amin, 4arshad ali shedayi, 5jin-tun zhang, 6xiaohang bai, 7brian gagosh nayyar, 8paras mazari of. It was found that the exposure of A549 cells to trilinolein resulted in the growth inhibition and the induction of apoptosis in a dose- and time- dependent manner. J. The more polar, Spinasterol exhibits antitumorigenic, anti-inflammatory [13], antimi. Amaranthus viridis grains were cultivated by National Horticultural Research Institute (NIHORT), Kano, Nigeria and matured grains were collected after 14 weeks (April to July, 2015). (+)-Catechin was the main phenolic compound identified in daylily flowers, accounting for about 74.11% of total phenolics. 4 0 obj On the growth and chlorophyll content in the leaves of Amaranthus viridis with sowing the seed once a month through the year. Result obtained from this research showed high rate of diversity. II. endobj Flowers densely clustered in elongate spikes. 46: 1181. and A. viridis. carcinoma (Bcap-37), human colon carcinoma (RKO), human hepatocellular carcinoma (SMMC-7721), human prostate carcinoma (PC3) and human erythroleukaemia (K562) cells. Administration of the extracts was applied to both laboratory animals at the doses of 200 and 400 mg/kg body weight, respectively. We showed that spinasterol increased the cellular resistance of HT22 cells to oxidative injury caused by the glutamate-induced cytotoxicity by extracellular signal-regulated kinase (ERK) pathway-dependent expression of HO-1. Both extracts significantly increased the BR. Amaranthus viridis L., known in the Philippines as Spinach Tagalog and Kolitis, is sold in the market as vegetable. These results suggest that spinasterol has a therapeutic potential against neurodegenerative diseases that are caused by oxidative stress and neuroinflammation. Weed Research, Japan, 21(1):6-11. Quantity and quality of Amaranthus grain from plants in temperate, cold and hot, and subtropical climates--A review. 2004). Intracellular reactive oxygen species seem to play a role in the trilinolein-induced apoptosis, since ROS were produced early in the trilinolein treatment. This weed is mostly found on roadsides and wastelands. This research aimed to study the effectiveness of red and green spinach as UVB protection for Btk. A. viridis contains several compounds like amino acids lysine, arginine, histidine, cystine, phenylalanine, leucine, isoleucine, valine, threonine, methionine, tyrosine etc. Moreover, the activity of PI3K/Akt was downregulated in trilinolein-treated cells. Determination of the constituents of these samples by NMR analyses indicated the presence of phytol 1a in sample 1, with lupeol 1b and β-amyrin 1c as impurities (< 10%) and sitosterol (2a) and stigmasterol (2b) in sample 2. �����4/5�<3�l�$��*3�Ȼ�.���i�����E[� Furthermore, spinasterol suppressed the lipopolysaccharide (LPS)-induced expression of pro-inflammatory enzymes and inflammatory mediators in BV2 microglia. A. Ojiako. In a low Ca2+ medium (0.5 mM Ca2+), these compounds suppressed the decrease of BR, which was induced by low Ca2+. 2006;Stintzing et al. The seed extracts exhibited superior antioxidant and antimicrobial activity [4]. A recent study reported that methanol extracts of A. viridis showed considerable antimicrobial activity against selected bacterial and fungal strains with MIC ranging from 179-645 μg/mL. 1. The objective of this review is to consider the phytoconstituents from six species under the genus Amaranthus (A. retroflexus, A. spinosus, A. viridis, A. caudatus, A. hypocondriacus and A. tricolor). Cinnamomum cebuense Kosterm (Lauraceae) is an endemic and endangered Philippine tree yielded used by local residents as remedy for stomach ache. It was concluded that A. viridis leaf and seed can be explored as a potential source for isolation of antioxidant and antimicrobial agents for uses in functional food and pharmaceuticals. Their structures were elucidated by extensive 1D S . The leaves of Amaranthus are a potential alternative source of betalains because of their betacyanin pigments, and they also show anticancer activity. %���� Information will be presented in tables for the convenience of readers, and many structures of natural products are presented. CERTIFICATE This is to certify that the dissertation work entitled “NEUROPHARMACOLOGICAL EFFECTS OF METHANOLIC EXTRACT OF LEAVES OF AMARANTHUS VIRIDIS.L IN RATS & MICE” submitted by Register The aim of this study was to investigate the levels of POPs in irrigation water, soil and in Amaranthus viridis (A. viridis) from different gardening sites in Kinshasa to evaluate the potential environmental and human health risks. afforded a 4:1 mixture of spinasterol (1a) and 24- However, the efficacy of this nanoformulation against weeds commonly found in crop cultures has not been tested yet. 2Chemistry Government Girls Degree College, Sheikh, Malton Mardan, Pakistan. Original article submitted March 24, 2013. 2 0 obj Four individual phenolics, such as (+)-catechin, chlorogenic acid, rutin and quercetin were identified and quantified by HPLC. %PDF-1.7 Abstract. Hence present investigation reveals the antinociceptive and antipyretic activities of methanolic extract of Amaranthus viridis. This review article is about plants of this family in general and in particular about Amaranthaceae plants of our region. Ikenaga T, Matuo M, Ohashi H, 1975. ... Phenolic compounds: Two phenolic compounds such as Amaranthine (20) and Isoamaranthine (21) bearing anti-malarial activities are known from the medicinal plant A. spinosus (Figure 4) (Hilou et al. The present study was conducted to evaluate the phenolics, antioxidant and antimicrobial activities of leaf and seed extracts from an edible herb namely Amaranthus viridis L. The extract yields of active components, produced using pure and aqueous methanol, from the leaves and seeds ranged from 5.4 to 6.0 and 2.4 to 3.7%, respectively. <> The methanol extract of buckwheat contained principally four flavonol glycosides: rutin, quercetin, kaempferol-3-rutinoside and a trace quantity of a flavonol triglycoside. Antimicrobial activity tests on sample 1 indicated that it was slightly ex Poiret Similar Species: Amaranthus spinosus L. Origin: probably native to Old World tropics, early introduction to Pacific Islands Weed Category: Broadleaves The flowers of Cucurbita maxima Duch. Distinguishing features. The inhibitory action of the extracts from C. sesamoides and L. taraxacifolia were greatest at high concentrations of 15 mg/ml when the virus had already penetrated the cell. Another study reported that after treatment with A. viridis methanol extract, normal and streptozotocin induced diabetic rats exhibited a significant increase in body weight and a decrease in blood glucose, total cholesterol, and serum triglycerides [3]. Full Length Research Paper Pharmacognostic evaluation of the Amaranthus viridis L. Musharaf Khan1*, Shahana Musharaf2, Mohammad Ibrar1 and Farrukh Hussain1 1Department of Botany, University of Peshawar, Pakistan. Keywords: ABTS, Amaranthus viridis, Antioxidants, Aqueous extract, Cancer, DPPH. All rights reserved. British Journal of Pharmaceutical Research, ISSN: 2231-2919,Vol. aureus, and Trichophyton mentagrophytes. research is to investigate the hydroponic (NFT, DFT, Aeroponic) efficiency on water use using Amaranthus viridis L. as the planted material. above sea level. Column chromatography was performed with, silica gel 60 (70–230 mesh), while TLC was performed with plastic backe, . been reported to have anticancer activities. It was inactive against Escherichia coli, Staphylococus �kI&�D��dt�pR�t��߿��?M���{|p����dBHY�������u5!VO)%<=Um�y%'�k����5��7�~N��M�����/���xt�VP^�zBXIaHՂ�S4�Y��dLE�BB0������8V�i]H�o8���M�ñq�(�� I1� ����F�D�K&&�.���ߋ�� 5ߗ�;mJ��3V2����;��O���Wt0y����᫋���O�{:��0;;�L�g{��*�Fxt��PEZRr1��,5�R+$��K����O^"N of Amaranthus viridis showed no evidence of single dose toxicity (2000 mg/kg) when studying acute toxicity. O. D. Omodamiro 1*, M. A. Jimoh 2 and P. U. Ezurike 1. R. K. Obi, I. I. Iroagba, O. C. Y. Ragasa, E. S. Javier, I. G. Tan. The results of the statistical analysis showed that MEAV had significant (p<0.01) dose dependent antinociceptive and antipyretic properties at 200 and 400 mg/kg. When compared with control, hydroxy-β-sanshool (1b) and xanthoxylin (2) stimulated 13–15 fold calcium uptake of the cultured myocardial cells, which might have caused the positive chronotropic effect. used in Nigeria as edible vegetables were tested for antiviral activities using the measles virus on Human Epidermoid carcinoma (HEP-2) cell line. Weed Research, Japan, 20(4):153-156 the need to isolate the individual compounds. Grain amaranth was an important crop for the preHispanic, New World civilizations. These were bioassayed with the micronucleus test and were found to be antimutagenic. is a fast-growing herb mainly cultivated in Asia, Africa, Latin America (Amin, Norazaidah, & Hainida, 2006). Column chromatography of the ethyl acetate extract of the leaves of Vitex parviflora yielded, among others, samples 1 and 2. Amaranthus viridis is a plant that is very widely distributed in our country, grows easily, and is eaten by low-income groups. endobj Amaranthaceae family is one of the largest and most diverse in the plant kingdom. Besides, the tested extracts showed considerable antimicrobial activity against selected bacterial and fungal strains with minimum inhibitory concentrations (MIC) ranging from 179-645 µg/ml. Earlier studies reported the isolation of quercetin and lutein [5] and rutin and β-carotene [6] from A. viridis. The extracts contained appreciable levels of total phenolic contents (1.03 to 3.64 GAE, g/100 g) and total flavonoid contents (18.4 – 5.42 QE, g/100 g) and also exhibited good 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity as revealed by IC 50 (14.25 -83.43 µg/ml). endobj The extensive discussion section will focus mainly (but not only) on studies of active compounds production. Trilinolein treatment induced the upregulation of pro-apoptotic Bax, downregulation of anti-apoptotic Bcl-2 expression, which was associated with the proteolytic activation of caspases and the concomitant degradation of poly(ADP-ribose) polymerase (PARP) protein. x��=َ9���[email protected]��W2��Q��>��]�م=r�\�i��R�ݞ?ڷ��m��~�2�gf�u���7�j)�"���d�f����>�����h�����;?��Ã��/fNj�Y�8? S. Kuznecovs, K. Jegina, I. Kuznecovs. Amaranthus viridis is an ecumenical species in the botanical family of Amaranthaceae, which has been traditionally used to treat several skin diseases along with some antilipidemic activities. Amaranthus spp. J. Amaranthus viridis is a vigorous, erect, branched, annual plant growing 10 - 100cm tall. Through bioassay directed fractionation of the. Botanical Name : Amaranthus viridis L. Common Name : Dhimbdo, Green Amaranth Plant Family : Amaranthaceae Plant Form : Herb Occurrence (Sectors) : 1, 5, 18, 27, 30 Occurrence (Special Areas) : Gujarat Forestry Research Foundation, Indroda Park, Sarita Udyan, Infocity About Amaranthus viridis Plant : Habit : Erect or diffuse annual unarmed herbs, simple or branched, 20 - 80cm tall. Overall, daylily flowers at opening stage possess the highest functional benefit and thus would be the appropriate harvesting stage in view of the nutritional consideration. RM�Wݣ���H�q��Zv"o�y�WO/�v�*����0SĵTr�NN�M��^����i�?���'�X}ß���_��]�bz��we������~�TͤpH^p8+����4��h �&�����y�+��n�� 19. Pigweed (Amaranthus viridis L.), belonging to the family Amaranthaceae, is commonly known with different names such as Amaranth, Slender amaranth, Chinese spinach, Caruru, and Tampala. Kesan penggunaan gentian mesokarpa terhadap pertumbuhan dan penghasilan bayam hijau (Amaranthus Viridis L.) This research is being done to study the effect of using a planting medium based on mesocarp fibre mixed with top soil to the growth and production of green spinach. Research and development opportuni-ties on nutritive and nutraceutical properties, produc-tion and commercialization, taxonomic evaluation and breeding perspectives were explored. Amaranthus cruentus: Milling characteristics distribution of nutrient within seed components, and the effects of temperature on nutritional quality. In addition to general chemical composition that was presented in previous cited publications, two more interesting articles did the same. Conclusions and future research recommendations are also presented. ... Council of Scientific and Industrial Research, New Delhi. Amaranthus viridis L. belongs to family (Amaranthaceae) commonly known as “Chowlai” is a common wild vegetable and weed of cultivation. A. viridis is a vigorous annual that grows up to around 1 m tall. In vitro Antioxidant Activity and Hypolipidemic Effects of an Ethanol Extract of Amaranthus viridis Leaves on Hyperlipidemic Wistar Albino Rats. The grains were wet cleaned and dried in a hot air oven (SM9053, Uniscope, UK) at 50°C for 8 hr. Amaranthaceae plants -medicinal activities Section C-Review AMARANTHACEAE PLANTS OF ISRAEL AND PALESTINE: MEDICINAL ACTIVITIES AND UNIQUE COMPOUNDS, A Comprehensive Review on the Phytoconstituents from Six Species of the Genus Amaranthus, Metabolites of the Vietnamese Plant Amaranthus viridis, Antinociceptive and Antipyretic Activities of Amaranthus Viridis Linn in Different Experimental Models, Virucidal potential of some edible Nigerian vegetables, Antimutagenic terpenes and sterols from Vitex parviflora, Secondary Metabolites of Cinnamomum cebuense, Antioxidant and antimicrobial activities of Chowlai (Amaranthus viridis L.) leaf and seed extracts, Trilinolein Inhibits Proliferation of Human Non-Small Cell Lung Carcinoma A549 Through the Modulation of PI3K/Akt Pathway, P9 Inhibition of P-glycoprotein by polyprenol in human breast cancer cells, Amasterol, an ecdysone precursor and a growth inhibitor from Amaranthus viridis, Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines, Natural Products Derived from Philippine Plants, A new lignan with anti-tumour activity from Polygonum perfoliatum L, Antioxidant properties and involved compounds of daylily flowers in relation to maturity. Compound 1 showed cytotoxicity against human mammary, The antioxidant properties of methanol extracts from daylily flowers during maturation were determined with antioxidant assays, including antioxidant activity, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, superoxide anion radical scavenging and reducing power. Extracts from four leaves: Ceratotheca sesamoides (Endl. The study concluded that the promising antioxidant capacities of A. viridis extract can further be utilized in various agricultural, pharmaceutical, and food applications. Amaranthus viridis Linn is a common summer weed found every where. and 2D NMR analyses. Amaranthus is a cosmopolitan genus of annual or short-lived perennial plants collectively known as amaranths. In view of the efficacy of these extracts in inhibiting the cytopathic effect (CPE) of measles virus without harming the host, the utilization of the extracts in the formulation of new antiviral drugs is strongly recommended especially when the availability and the very low cost of these vegetables are considered. In this study, we report the efficacy of spinasterol in effectively modulating the regulation of antioxidative and anti-inflammatory activity through the upregulation of heme oxygenase (HO)-1 in murine hippocampal HT22 cells and BV2 microglia. Significant variation in, An analytical method for flavonoids present in the seed extract of buckwheat (Fagopyrum esculentum Moench, Polygonaceae), using HPLC and a photodiode array detector and interfaced to an electrospray ionisation mass spectrometer, has been developed. K . In a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. stream A survey study for the use of pesticides and fertilizers was carried out with 740 market gardeners. Original-research-article. The object of research is the amaranth plant of three species – forage (Amaranthus caudatus L.), grain (Amaranthus cruentus L.) and decorative (Amaran-thus hipochondriacus L.). Food Sci. Join ResearchGate to find the people and research you need to help your work. <>/Metadata 1103 0 R/ViewerPreferences 1104 0 R>> Structural information about the flavonols was obtained from the retention time characteristics, the UV-visible spectra and the mass spectra without, In the course of our studies on naturally occurring cardioactive agents, we investigated the effects of water and methanol extracts of a Chinese crude drug “Huajiao” the dried fruit of Zanthoxylum bungeanum, on the spontaneous beating rate (BR) of embryonic mouse myocardial cell sheets in culture. 3 0 obj Methanolic extract of whole plant of Amaranthus viridis L (MEAV), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. The subacute toxicity study of the aqueous extract of A. viridis at doses of 200, 400 and 600 mg/kg showed no signs of toxicity on biochemical, hematological or histological parameters. The website also provides access to a database and images of plants photos and herbarium specimens found at … R o y, A . Hyperin (4) and quercitrin (6) did not affect calcium uptake of the myocardial cells, Na+–K+ ATPase activity or Ca2+-ATPase activity of sarcoplasmic reticulum. 1. : 6. Year 1986 P. C h a k r a b o r t y. 4. <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 595.32 841.92] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>
2020 amaranthus viridis research